孙莉萍 副教授（材料学院）

个人简介

孙莉萍副教授，博士，硕士生导师。先后毕业于同济医科大学（1992-1998）、德国德累斯顿工业大学（博士，2004）。2004年起任厦门大学生物医学工程研究中心助理教授、2010年任厦门大学生物材料系副教授。2011至2013年在以色列魏茨曼科学研究所（Weizmann Institute of Science）从事访问学者研究。

孙莉萍副教授长期从事纳米材料与生物医学相关的研究，近年来先后主持国家自然科学基金2项，在Analytical Chemistry、Nanotechnology、Small、Electrochimica Acta、Biosensors & Bioelectronics、Medicinal Chemistry Communications、Bioorganic & Medicinal Chemistry等学术刊物上共发表了SCI收录论文20多篇，受邀参编了Transworld Research Network出版社出版的《Nanostructed Materials for Biomedical Applications》(ISBN: 978-81-7895-397-7)。已获授权中国发明专利4项。

孙莉萍副教授目前主要研究方向包括：（1）构建多功能纳米材料，在不同靶向生物分子的帮助下，特异性检测肿瘤细胞、DNA突变和蛋白质异常折叠。（2）探讨纳米材料与生物大分子的相互作用，从而实现对生物分子的识别和诊断。（3）发展新型胶原材料，用于体外蛋白质表达的支架。

电子邮箱: sunliping@xmu.edu.cn

主要研究与教学领域：

研究领域：

(1) 纳米材料在生物检测领域的应用

(2) 纳米材料与生物分子的相互作用

(3) 胶原的设计和体外蛋白质的表达

教学领域：

(1)细胞生物学，生物医学工程专业硕士研究生必修课

(2)分子遗传学，生物医学工程专业硕士研究生选修课

(3)生物化学实验，本科生课程

个人经历

工作经历

1998-2000 广州儿童医院住院医师

2000-2003 德累斯顿工业大学医学系遗传实验室博士工作

2004-2010 厦门大学生物医学工程研究中心讲师

2010至今 厦门大学生物医学工程研究中心副教授

2011-2013 以色列魏茨曼科学研究所访问学者

教育经历

2000.10-2003.08 德国德累斯顿工业大学医学系

1992.09-1998.07 同济医科大学6年制德语医学专业

代表著作

近5年发表的论文：

1.J Jia, LP Sun*, N Hu, GM Huang, J Weng. Graphene enhances the specificity of the polymerase chain reaction. Small. 2012. 8(13):2011-2015.

2.ZW Zhang, J Jia, YY Ma, YN Sun, YQ Lai, J Weng, LP Sun*. Microwave-assisted one-step rapid synthesis of folic acid modified gold nanoparticles for cancer cells targeting and detection.Medicinal Chemistry Communications. 2011. 2.1079-1082.

3.W Yang, LP Sun*, LY Chen, J Weng, QQ Zhang. Probing the interaction of bovine haemoglobin with gold nanoparticles. IET Nanobiotechnology. 2011.6(1):26-32.

3.YQ Lai, YY Ma, LP Sun*, J Jia, J Weng, QQ Zhang. A highly selective electrochemical biosensor for Hg2+ using hemin as a redox indicator. Electrochimica Acta. 2011. 56(9):3153-3158.

4.LP Sun*, S Wang, ZW Zhang, YY Ma, YQ Lai, J Weng, QQ Zhang. Interaction of gold nanoparticles with Pfu DNA polymerase and effect on polymerase chain reaction. IET Nanobiotechnology. 2011.5(1):20-24.

5.J Weng, ZW Zhang, LP Sun, JA Wang. High sensitive detection of cancer cell with a folic acid-based diamond electrode using an AC impedimetric approach. Biosensors & Bioelectronics. 2011. 26(5):1847-1852.

6.ZW Zhang, J Jia, YQ Lai, YY Ma, J Weng, LP Sun*. Conjugating folic acid to gold nanoparticles through glutathione for targeting and detecting cancer cells. Bioorganic & Medicinal Chemistry. 2010.18(15):5528-5534.

7.LP Sun*, S Wang, ZW Zhang, XY Wang, QQ Zhang. Biological evaluation of collagen-chitosan scaffolds for dermis tissue engineering. Biomedical Materials. 2009.4(5):055008 (6pp).

8.LP Sun*, ZW Zhang, Wang S, JF Zhang, H Li, L Ren, J Weng, QQ Zhang. Effect of pH on the interaction of gold nanoparticles with DNA and application in the detection of human p53 gene mutation. Nanoscale Research Letters. 2009.4(3):216-220.

9.LP Sun*, JF Zhang, H Li, XY Wang, ZW Zhang, S Wang, QQ Zhang. The interaction between gold nanoparticles and ssDNA. Chemical Journal of Chinese Universities. 2009. 30(1):95-99.

10.J Weng, JF Zhang, H Li, LP Sun*, CH Lin, QQ Zhang. Label-free DNA sensor by boron-doped-diamond electrode using an AC impedimetric approach. Analytical Chemistry. 2008. 80(18):7075-7083.

11.JF Zhang, LP Sun*, H Li, XY Wang, QQ Zhang. Gold nanoparticles application in gene mutation detection and SNP analysis. Chinese Journal of Biochemistry and Molecular Biology. 2008. 24(6):489-495.

12.J Li, LP Sun*, SF Ye, JF Zhang, H Li, XY Wang, M Guan, QQ Zhang. Study on tissue engineered dermal substitutes. Journal of Xiamen University (Natural Science). 2008. 47(3):387-391.

13.XY Wang, LP Sun*, JF Zhang, H Li, WQ Lv, QQ Zhang. F-box proteins and their functions.Chinese Bulletin of Life Sciences. 2008. 20(5): 807-811.

14.L Ren, XL Huang, B Zhang, LP Sun, QQ Zhang. Cisplatin loaded Au-Au2S nanoparticles for potential cancer therapy: Cytotoxicity, in Vitro Carcinogenicity, and cellular uptake. Journal of Biomedical Materials Research A. 2008. 85A(3):787-796.

  1. XL Huang, B Zhang, L Ren, SF Ye, LP Sun, QQ Zhang, MC Tan, GM Chow. In vivo toxic studies and biodistribution of near infrared sensitive Au-Au2S nanoparticles as potential drug delivery carriers. Journal of Materials Science. 2008. 19 (7):2581-2588.

  2. L Wang, B Yu, L Ren, LP Sun, QQ Zhang. Microsphere-integrated gelatin-siloxane hybrid scaffolds for bone tissue engineering: in vitro bioactivity & antibacterial activity. Frontiers of Materials Science in China. 2008. 2(2): 102-108.

  3. ZY Wang, Y Zhao, L Ren, LH Jin, LP Sun, P Yin, YF Zhang, QQ Zhang. Novel gelatin–siloxane nanoparticles decorated by Tat peptide as vectors for gene therapy. Nanotechnology. 2008. 19(44) :445103 (14pp)